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    How do cells organize their organelles and cytoskeleton under shape constraint?

    Can we force them to evolve in a defined space?

    These two different questions from the point of view of their scientific objective lead to the same technical problem. Unlike the homogeneous functionalization described above, the solution here will be to carry out a selective functionalization of the substrate, i.e. of very defined shapes and areas. This will be achieved by micro-printing of adhesion molecules in order to draw shapes such as squares, straight or broken lines ... The micro-printing is developed in collaboration with Fabienne Régnier (Clotilde Randriamampita's team) and uses two techniques: by "ink pad" (Figure 1) and by "deep UV" (Figure 2). Figure 3 illustrates two examples of microprinting applications.