Institut de recherche biomédicale
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    Publications de l'équipe : Pharmacologie fonctionnelle et physio-pathologie des recepteurs

    122 publication(s) trouvée(s)

    • Vauthier, V., Roujeau, C., Chen, P., Sarkis, C., Migrenne, S., Hosoi, T., Ozawa, K., Rouille, Y., Foretz, M., Mallet, J., Launay, J.-M., Magnan, C., Jockers, R., Dam, J. Endospanin1 affects oppositely body weight regulation and glucose homeostasis by differentially regulating central leptin signaling Molecular Metabolism 2017; 6(1):
    • Sokolina, K., Kittanakom, S., Snider, J., Kotlyar, M., Maurice, P., Gandia, J., Benleulmi-Chaachoua, A., Tadagaki, K., Oishi, A., Wong, V., Malty, R. H., Deineko, V., Aoki, H., Amin, S., Yao, Z., Morato, X., Otasek, D., Kobayashi, H., Menendez, J., Auerbach, D., Angers, S., Przulj, N., Bouvier, M., Babu, M., Ciruela, F., Jockers, R., Jurisica, I., Stagljar, I. Systematic protein-protein interaction mapping for clinically relevant human GPCRs Mol Syst Biol 2017; 13(3):918
    • Belacel-Ouari, M., Zhang, L., Hubert, F., Assaly, R., Gerbier, R., Jockers, R., Dauphin, F., Lechene, P., Fischmeister, R., Manoury, B., Leblais, V. Influence of cell confluence on the cAMP signalling pathway in vascular smooth muscle cells Cell Signal 2017; 35:118-128
    • Gbahou, F., Cecon, E., Viault, G., Gerbier, R., Jean-Alphonse, F., Karamitri, A., Guillaumet, G., Delagrange, P., Friedlander, R. M., Vilardaga, J. P., Suzenet, F., Jockers, R. Design and validation of the first cell-impermeant melatonin receptor agonist Br J Pharmacol 2017; 174(14):2409-2421
    • Oishi, A., Karamitri, A., Gerbier, R., Lahuna, O., Ahmad, R., Jockers, R. Orphan GPR61, GPR62 and GPR135 receptors and the melatonin MT2 receptor reciprocally modulate their signaling functions Sci Rep 2017; 7(1):8990
    • Suofu, Y., Li, W., Jean-Alphonse, F. G., Jia, J., Khattar, N. K., Li, J., Baranov, S. V., Leronni, D., Mihalik, A. C., He, Y., Cecon, E., Wehbi, V. L., Kim, J., Heath, B. E., Baranova, O. V., Wang, X., Gable, M. J., Kretz, E. S., Di Benedetto, G., Lezon, T. R., Ferrando, L. M., Larkin, T. M., Sullivan, M., Yablonska, S., Wang, J., Minnigh, M. B., Guillaumet, G., Suzenet, F., Richardson, R. M., Poloyac, S. M., Stolz, D. B., Jockers, R., Witt-Enderby, P. A., Carlisle, D. L., Vilardaga, J. P., Friedlander, R. M. Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release Proc Natl Acad Sci U S A 2017; 114(38):E7997-E8006
    • Benleulmi-Chaachoua, A., Chen, L., Sokolina, K., Wong, V., Jurisica, I., Emerit, M. B., Darmon, M., Espin, A., Stagljar, I., Tafelmeyer, P., Zamponi, G. W., Delagrange, P., Maurice, P., Jockers, R. Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons J Pineal Res 2016; 60(1):95-108
    • Chandra, V., Karamitri, A., Richards, P., Cormier, F., Ramond, C., Jockers, R., Armanet, M., Albagli-Curiel, O., Scharfmann, R. Extracellular acidification stimulates GPR68 mediated IL-8 production in human pancreatic beta cells Sci Rep 2016; 6:25765
    • Jockers, R., Delagrange, P., Dubocovich, M. L., Markus, R. P., Renault, N., Tosini, G., Cecon, E., Zlotos, D. P. Update on melatonin receptors: IUPHAR Review 20 Br J Pharmacol 2016; 173(18):2702-25
    • Bonnefond, A., Karamitri, A., Jockers, R., Froguel, P. The Difficult Journey from Genome-wide Association Studies to Pathophysiology: The Melatonin Receptor 1B (MT2) Paradigm Cell Metab 2016; 24(3):345-7
    • Kellermann, G., Kaiser, M., Dingli, F., Lahuna, O., Naud-Martin, D., Mahuteau-Betzer, F., Loew, D., Segal-Bendirdjian, E., Teulade-Fichou, M. P., Bombard, S. Identification of human telomerase assembly inhibitors enabled by a novel method to produce hTERT Nucleic Acids Res 2015; 43(15):e99
    • Kamal, M., Gbahou, F., Guillaume, J. L., Daulat, A. M., Benleulmi-Chaachoua, A., Luka, M., Chen, P., Kalbasi Anaraki, D., Baroncini, M., Mannoury la Cour, C., Millan, M. J., Prevot, V., Delagrange, P., Jockers, R. Convergence of Melatonin and Serotonin (5-HT) Signaling at MT2/5-HT2C Receptor Heteromers J Biol Chem 2015; 290(18):11537-46
    • Hamr, S. C., Wang, B., Swartz, T. D., Duca, F. A. Does nutrient sensing determine how we "see" food? Curr Diab Rep 2015; 15(6):604
    • Alkan, M., Machavoine, F., Rignault, R., Dam, J., Dy, M., Thieblemont, N. Histidine Decarboxylase Deficiency Prevents Autoimmune Diabetes in NOD Mice Journal of Diabetes Research 2015; 2015:965056
    • Cecon, E., Chen, M., Marcola, M., Fernandes, P. A., Jockers, R., Markus, R. P. Amyloid beta peptide directly impairs pineal gland melatonin synthesis and melatonin receptor signaling through the ERK pathway FASEB J 2015; 29(6):2566-82
    • Ahmad, R., Wojciech, S., Jockers, R. Hunting for the function of orphan GPCRs - beyond the search for the endogenous ligand Br J Pharmacol 2015; 172(13):3212-28
    • Dam, J., Jockers, R., Guerre-Millo, M., Clement, K. Leptin receptors and mechanism of action 2015; 23:15-24
    • Kim, T. H., Choi, D. H., Vauthier, V., Dam, J., Li, X., Nam, Y. J., Ko, Y., Kwon, H. J., Shin, S. H., Cechetto, J., Soloveva, V., Jockers, R. Anti-Obesity Phenotypic Screening Looking to Increase OBR Cell Surface Expression J Biomol Screen 2014; 19(1):88-99
    • Jockers, R. Comment on the Frontiers in Endocrinology Research Topic Ebook on BRET. Front Endocrinol 2014; 5(3):10.3389
    • Jockers, R. Comment on "The Use of BRET to Study Receptor-Protein Interactions" Front Endocrinol (Lausanne) 2014; 5:3