Institut de recherche biomédicale
     
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    Publications de l'équipe : Pharmacologie fonctionnelle et physio-pathologie des recepteurs

    133 publication(s) trouvée(s)

    • Owino, S., Sanchez-Bretano, A., Tchio, C., Cecon, E., Karamitri, A., Dam, J., Jockers, R., Piccione, G., Noh, H. L., Kim, T., Kim, J. K., Baba, K., Tosini, G. Nocturnal activation of melatonin receptor type 1 signaling modulates diurnal insulin sensitivity via regulation of PI3K activity J Pineal Res 2018; 64(3):e12462
    • Wojciech, S., Ahmad, R., Belaid-Choucair, Z., Journe, A. S., Gallet, S., Dam, J., Daulat, A., Ndiaye-Lobry, D., Lahuna, O., Karamitri, A., Guillaume, J. L., Do Cruzeiro, M., Guillonneau, F., Saade, A., Clement, N., Courivaud, T., Kaabi, N., Tadagaki, K., Delagrange, P., Prevot, V., Hermine, O., Prunier, C., Jockers, R. The orphan GPR50 receptor promotes constitutive TGFbeta receptor signaling and protects against cancer development Nat Commun 2018; 9(1):1216
    • Roujeau, C., Jockers, R., Dam, J. [Hypothalamic endospanin 1 dissociates obesity from type 2 diabetes] Med Sci (Paris) 2018; 34(4):288-291
    • Oishi, A., Cecon, E., Jockers, R. Melatonin Receptor Signaling: Impact of Receptor Oligomerization on Receptor Function Int Rev Cell Mol Biol 2018; 338:59-77
    • Igonet, S., Raingeval, C., Cecon, E., Pucic-Bakovic, M., Lauc, G., Cala, O., Baranowski, M., Perez, J., Jockers, R., Krimm, I., Jawhari, A. Enabling STD-NMR fragment screening using stabilized native GPCR: A case study of adenosine receptor Sci Rep 2018; 8(1):8142
    • Bignon, Y., Alekov, A., Frachon, N., Lahuna, O., Jean-Baptiste Doh-Egueli, C., Deschenes, G., Vargas-Poussou, R., Lourdel, S. A novel CLCN5 pathogenic mutation supports Dent disease with normal endosomal acidification Hum Mutat 2018; 39(8):1139-1149
    • Ahmad, R., Wojciech, S., Jockers, R. GPR50 in TGFbeta signaling and breast cancer Oncoscience 2018; 5(5-6):157-158
    • Cecon, E., Oishi, A., Jockers, R. Melatonin receptors: molecular pharmacology and signalling in the context of system bias Br J Pharmacol 2018; 175(16):3263-80
    • Clement, N., Renault, N., Guillaume, J. L., Cecon, E., Journe, A. S., Laurent, X., Tadagaki, K., Coge, F., Gohier, A., Delagrange, P., Chavatte, P., Jockers, R. Importance of the second extracellular loop for melatonin MT1 receptor function and absence of melatonin binding in GPR50 Br J Pharmacol 2018; 175(16):3281-97
    • Karamitri, A., Plouffe, B., Bonnefond, A., Chen, M., Gallion, J., Guillaume, J. L., Hegron, A., Boissel, M., Canouil, M., Langenberg, C., Wareham, N. J., Le Gouill, C., Lukasheva, V., Lichtarge, O., Froguel, P., Bouvier, M., Jockers, R. Type 2 diabetes-associated variants of the MT2 melatonin receptor affect distinct modes of signaling Sci Signal 2018; 11(545):aan6622
    • Auriau, J., Roujeau, C., Belaid Choucair, Z., Oishi, A., Derviaux, C., Roux, T., Trinquet, E., Hermine, O., Jockers, R., Dam, J. Gain of affinity for VEGF165 binding within the VEGFR2/NRP1 cellular complex detected by an HTRF-based binding assay Biochem Pharmacol 2018; 158:45-59
    • Vauthier, V., Roujeau, C., Chen, P., Sarkis, C., Migrenne, S., Hosoi, T., Ozawa, K., Rouille, Y., Foretz, M., Mallet, J., Launay, J.-M., Magnan, C., Jockers, R., Dam, J. Endospanin1 affects oppositely body weight regulation and glucose homeostasis by differentially regulating central leptin signaling Molecular Metabolism 2017; 6(1):
    • Sokolina, K., Kittanakom, S., Snider, J., Kotlyar, M., Maurice, P., Gandia, J., Benleulmi-Chaachoua, A., Tadagaki, K., Oishi, A., Wong, V., Malty, R. H., Deineko, V., Aoki, H., Amin, S., Yao, Z., Morato, X., Otasek, D., Kobayashi, H., Menendez, J., Auerbach, D., Angers, S., Przulj, N., Bouvier, M., Babu, M., Ciruela, F., Jockers, R., Jurisica, I., Stagljar, I. Systematic protein-protein interaction mapping for clinically relevant human GPCRs Mol Syst Biol 2017; 13(3):918
    • Belacel-Ouari, M., Zhang, L., Hubert, F., Assaly, R., Gerbier, R., Jockers, R., Dauphin, F., Lechene, P., Fischmeister, R., Manoury, B., Leblais, V. Influence of cell confluence on the cAMP signalling pathway in vascular smooth muscle cells Cell Signal 2017; 35:118-128
    • Gbahou, F., Cecon, E., Viault, G., Gerbier, R., Jean-Alphonse, F., Karamitri, A., Guillaumet, G., Delagrange, P., Friedlander, R. M., Vilardaga, J. P., Suzenet, F., Jockers, R. Design and validation of the first cell-impermeant melatonin receptor agonist Br J Pharmacol 2017; 174(14):2409-2421
    • Oishi, A., Karamitri, A., Gerbier, R., Lahuna, O., Ahmad, R., Jockers, R. Orphan GPR61, GPR62 and GPR135 receptors and the melatonin MT2 receptor reciprocally modulate their signaling functions Sci Rep 2017; 7(1):8990
    • Suofu, Y., Li, W., Jean-Alphonse, F. G., Jia, J., Khattar, N. K., Li, J., Baranov, S. V., Leronni, D., Mihalik, A. C., He, Y., Cecon, E., Wehbi, V. L., Kim, J., Heath, B. E., Baranova, O. V., Wang, X., Gable, M. J., Kretz, E. S., Di Benedetto, G., Lezon, T. R., Ferrando, L. M., Larkin, T. M., Sullivan, M., Yablonska, S., Wang, J., Minnigh, M. B., Guillaumet, G., Suzenet, F., Richardson, R. M., Poloyac, S. M., Stolz, D. B., Jockers, R., Witt-Enderby, P. A., Carlisle, D. L., Vilardaga, J. P., Friedlander, R. M. Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release Proc Natl Acad Sci U S A 2017; 114(38):E7997-E8006
    • Benleulmi-Chaachoua, A., Chen, L., Sokolina, K., Wong, V., Jurisica, I., Emerit, M. B., Darmon, M., Espin, A., Stagljar, I., Tafelmeyer, P., Zamponi, G. W., Delagrange, P., Maurice, P., Jockers, R. Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons J Pineal Res 2016; 60(1):95-108
    • Chandra, V., Karamitri, A., Richards, P., Cormier, F., Ramond, C., Jockers, R., Armanet, M., Albagli-Curiel, O., Scharfmann, R. Extracellular acidification stimulates GPR68 mediated IL-8 production in human pancreatic beta cells Sci Rep 2016; 6:25765
    • Jockers, R., Delagrange, P., Dubocovich, M. L., Markus, R. P., Renault, N., Tosini, G., Cecon, E., Zlotos, D. P. Update on melatonin receptors: IUPHAR Review 20 Br J Pharmacol 2016; 173(18):2702-25
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