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    APCOD project selected by the ANR:

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    a collaboration between the Institut Cochin, the Cochin hospital and the Saint-Louis hospital. Team Jean-Daniel Chiche & Pierre-Régis Burgel

    APCOD project selected by the ANR RA-Covid-19: a collaboration between the Institut Cochin (Chiche-Burgel team), the Cochin hospital (medical ICU) and the Saint-Louis hospital (INSERM U976)

     

    On April 15th 2020, the ANR launched the call RA-Covid-19 (Research-Action Covid-19) to support projects with possible implementation in the society within the next 3 to 12 months. The APCOD project, coordinated by Vassili Soumelis (Saint-Louis Hospital) and Frédéric Pène (Institut Cochin) was one of the 6 projects selected from the first assessment wave of 32 proposals on June 2nd 2020.

     

    A better comprehension of the immune pathology of COVID-19 is the prerequisite step to identify new biomarker-based therapeutic strategies with significant clinical impact in severe COVID-19 disease. The APCOD project entitled “Antigen-presenting cells in COVID-19 disease at single-cell resolution” aims at studying the diversity of antigen-presenting cell subsets, their underlying molecular and functional characteristics, and the cellular networks involved in severe SARS-CoV-2 infection. It relies on complementary expertise in septic immune response and characterization of antigen-presenting cells.

     

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