Institut de recherche biomédicale
     

    Publications

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    1. SchiroliG, Conti A, Ferrari S, della Volpe L, Jacob A, Albano L, Beretta S, Calabria A, Vavassori V, Gasparini P, Salataj E, Ndiaye-Lobry D, Brombin C, Chaumeil J, Montini E, Merelli I, Genovese P, Naldini L, Di Micco R (2019) Precise Gene Editing Preserves Hematopoietic Stem Cell Function Following Transient p53-Mediated DNA Damage Response. Cell Stem Cell, 24:1-15. https://doi.org/10.1016/j.stem.2019.02.019
    2. Roch B, Abramowski V, Chaumeil J, de Villartay J-P (2019). Cernunnos/Xlf results in suboptimal V(D)J recombination and impaired lymphoid development in mice. Front Immunol, 10:443. https://doi.org/10.3389/fimmu.2019.00443
    3. Barros de Andrade e Sousa L, Jonkers I, Syx L, Chaumeil J, Picard C, Foret B, Chen C-J, Lis JT, Heard E, Schulz EG, Marsico A. (2019) Kinetics of Xist-induced gene silencing can be predicted from combinations of epigenetic and genomic features. BioRxiv https://doi.org/10.1101/510198
    4. Souyris M, Mejia JE, Chaumeil J, Guéry JC. (2018) Female predisposition to TLR7-driven autoimmunity: gene dosage and the escape from X chromosome inactivation. Semin Immunopathol, 41(2):153-164. https://doi.org/10.1007/s00281-018-0712-y
    5. Souyris M, Cenac C, Azar P, Daviaud D, Canivet A, Grunenwald S, Pienkowski C, Chaumeil J, Mejia JE, Guéry JC. (2018) TLR7 escapes from X chromosome inactivation in immune cells. Science Immunology, 3(19), pii: eaap8855. https://doi.org/10.1126/sciimmunol.aap8855
    6. Proudhon C, Hao B, Raviram R, Chaumeil J, Skok JA. (2015) Long-Range Regulation of V(D)J Recombination. Adv Immunol, 128:123-82. https://doi.org/10.1016/bs.ai.2015.07.003
    7. Chaumeil J, Skok JA. (2013) A new take on V(D)J recombination: transcription driven nuclear and chromatin reorganization in RAG-mediated cleavage. Front Immunol, 4:423. https://doi.org/10.3389/fimmu.2013.00423
    8. Rocha PP, Chaumeil J, Skok JA. Molecular Biology. (2013) Finding the right partner in a 3D genome. Science, 342(6164):133-4. https://doi.org/10.1126/science.1246106
    9. Chaumeil J, Micsinai M, Ntziachristos P, Roth DB, Aifantis I, Kluger Y, Deriano L, Skok JA. (2013) The RAG2 C-terminus and ATM protect genome integrity by controlling antigen receptor gene cleavage. Nature Comm, 31;4:2231. https://doi.org/10.1038/ncomms3231
    10. Chaumeil J*, Micsinai M, Skok JA. (2013) Combined Immunofluorescence And DNA FISH on 3D-preserved Interphase Nuclei to Study Changes in 3D Nuclear Organization. J Vis Exp, 72. e50087. https://doi.org/10.3791/50087
    11. Chaumeil J, Micsinai M, Ntziachristos P, Deriano L, Wang JMH, Ji Y, Nora E, Rodesch MJ, Jeddeloh JA, Kluger Y, Aifantis I, Schatz DG, Skok JA. (2013) Higher-order looping and nuclear organization of Tcra facilitate targeted RAG cleavage and regulated rearrangement in recombination centers. Cell Reports, 3(2):359-370. https://doi.org/10.1016/j.celrep.2013.01.024 (‘Leading Edge’ in Cell, 2013;152(6))
    12. Chaumeil J, Skok JA. (2012) The role of CTCF in regulating V(D)J recombination. Curr Opin Immun, 24(2):153-9. https://doi.org/10.1016/j.coi.2012.01.003
    13. Deriano L, Chaumeil J, Coussens M, Multani A, Chou YF, Alekseyenko AV, Chang S, Skok JA, Roth DB. (2011) The RAG2 C terminus suppresses genomic instability and lymphomagenesis. Nature, 471(7336):119-23. https://doi.org/10.1038/nature09755