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    Genomic analyses of human organ development

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    Séminaire de l'Institut Cochin

    Jeudi 11 octobre 2018 - 12h00 - Salle de conférence Rosalind Franklin, 2ème étage

     

    Neil Hanley
    Neil Hanley

    Professor of Medicine, University of Manchester, UK
    Director of Research & Innovation, Manchester University NHS Foundation Trust, UK

     

     invité par Raphaël Scharfmann

    Institut Cochin, 22 rue Méchain, 75014 Paris

     

    Résumé

     Neil Hanley is Professor of Medicine at the University of Manchester and Clinical Endocrinologist at the Manchester University NHS Foundation Trust where he is also Director of Research & Innovation. He has spent much of the last 20 years studying how a number of human organs develop by researching primary human material. This focus on organogenesis has included the pancreas, liver and adrenal gland amongst other tissues. Recently, he has been probing the hypothesis that broad interrogation across many organs leads to precise knowledge of how development is orchestrated in any one site. Some of this work has been published (e.g. Gerrard et al, eLife 2016). In his talk he will update on this study and discuss new unpublished data on epigenomic regulation of organogenesis, including its relevance to developmental disorders in patients.

     

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