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    Antigen-specific immunotherapy for autoimmune diseases

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    Séminaire de l'Institut Cochin

    Lundi 24 septembre 2018 - 12h00 - Salle de conférence Rosalind Franklin, 2ème étage

     


    Ranjeny Thomas

    The University of Queensland Diamantina Institute, Australia

     

     invitée par Anne Hosmalin

    Institut Cochin, 22 rue Méchain, 75014 Paris

     

    Résumé

    Professor Thomas’ research is focused on the study of the biology and clinical use of human dendritic cells in autoimmune disease. It has explored basic mechanisms of immunity and dendritic cell function in autoimmune disease.

    Professor Thomas is a graduate of the University of Western Australia. She received her MBBS in 1984, and then trained in Perth as a rheumatologist. She commenced a research fellowship with Peter Lipsky at Southwestern Medical Center, University of Texas in 1990, where she first identified and characterised human circulating dendritic cell precursors. She is now Professor of Rheumatology at University of Queensland, Translational Research Institute, consultant Rheumatologist at Princess Alexandra Hospital and fellow of the Australian Academy of Health and Medical Sciences.

    Her research is focussed on the study of autoimmune disease and restoration of tolerance. Through this work, she developed and tested the first rheumatoid arthritis vaccine. She has also contributed major insights into the pathogenesis of spondyloarthropathy and autoimmune diabetes, leading to the development of disease biomarkers and innovative immunotherapies. Ranjeny is founder and a director of the spin-off company, Dendright, which is developing antigen-specific (personalised) immunotherapy and companion biomarkers to prevent and treat rheumatoid arthritis. She is funded by the Juvenile Diabetes Research Foundation to develop antigen-specific immunotherapy for children with type 1 diabetes

     

    Quelques publications

     

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